Are you stuck with your research??

e-nnovation Life Sciences is your one stop solution for all your research related queries. Our researchers invest most of their time in preparation of material required to start the actual research. This leads to considerable delay in finalizing specific projects. Our goal is to meet these challenges and transforming them into opportunities.

e-nnovation life science identify innovative technologies ,engineered products and reliable partners  around the world that offers specific & considerable advantage over existing products, technologies & services available for our bio researchers as of now.

To meet these challenges, we at e-nnovation Life Sciences provide the largest collection of pre-made clones i.e. more than 20,000 including cDNA, expression ready ORF, RNAi and genomic libraries in Human, mouse, drosophila, Xenopus, Zebrafish, C.elegans amd many more model organisms. We also have a wide range of validated antibodies. Explore the range available with us.

• Option of individual pre-made clones, whole clone libraries or customized libraries are available

• Sequence verification available

• Plasmid preparation service available

• Fast turnaround time

• Easy to search using GenomeCUBE, the search engine

• Customization of project available via our in-house expertise

• For more information, Write us at [email protected] or contact- 9711347133

Introduction

Genome Editing is the ability to make specific changes at targeted genomic sites and is of fundamental importance to researchers in biology and medicine. Two genome editing technologies have emerged recently that exploit bacterial systems for plant pathogenesis or adaptive immunity:

1. TALEN (Transcription Activator-Like Effector Nucleases) 2. CRISPR (Clustered, Regularly Interspaced, Short Palindromic Repeats)

Applications

a) gene knockout

b) transgene knock-in, gene tagging

c) correction of genetic defects

Both the technologies use endonucleases that initiate double-strand breaks (DSBs) at virtually any genomic target sequence. While both technologies are popular, the decision to choose one technology over the other is not always clear. Therefore, depending on several factors such as Specificity, Target site selection, efficiency and ease of design, one can choose the best suited technology.

What is CRISPR?

CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. CRISPR sequences were originally identified in the Escherichia coli (E. coli) genome, and were found to function as part of an RNA-based adaptive immune system to target and destroy genetic parasites at the DNA level.

What is TALEN?

TALENs operate on almost the same principle as ZFNs. TALENs are fusions of transcription activator-like (TAL) proteins and a FokI nuclease. TAL proteins are composed of 33-34 amino acid repeating motifs with two variable positions that have a strong recognition for specific nucleotides (Deng et al., 2014). By assembling arrays of these TALs and fusing them to a FokI nuclease, specific cutting of the genome can be achieved. When two TALENs bind and meet, the FokI domains induce a double-strand break which can inactivate a gene, or can be used to insert DNA of interest (Cermak et al., 2011). TALENs are more specific than ZFNs, the monomers don’t have the cross-reactivity problem that plagued ZFN researchers. This simplicity has facilitated automation of TALEN construction (Reyon et al., 2012). On the downside, since a TAL is needed for each nucleotide, TALENs are larger and somewhat harder to deliver than ZFNs.

Sequencing the genome via traditional methods is a labor-intensive, time-consuming and slow process. With the advancement in the era, the field of sequencing has advanced its methodology and led us to the world of Next Generation Sequencing.

eLS in association with SBS (authorised service provider for Illumina) provides various NGS technologies depending on the need of the customer-

• HiSeq

• MiSeq

• NextSeq

eLS provides the world-class cryostorage containers to the customers designed for storing biological materials, human or animal cells at temepratures as low as -196ºC. 

Cryostorage containers include

-Cryovials: (2mL) used for cryostoring the liquid biological material. 

-Cryoboxes: which can be used for transportation of biological material under cryogenic conditions. 

With the aim to fulfill the basic and advanced needs of a research laboratory, we provide our customers with the best graded, highly sensitive and efficient pipettes and tips of varying volumes (1000μl, 200μl, 10μl) from the best brands around the world.

We have an exclusive range of primary, secondary, polyclonal, monoclonal and customized antibodies are available at the best prices.

Why antibodies from e-nnovation Life Sciences? 

• Comprehensive collection of antibodies

• Quality performance guaranteed                                        

• 24*7 available technical support

• On time delivery

WE PROVIDE THE BEST QUALITY DROSOPHILA RESEARCH PRODUCTS WHICH ARE PRECISELY MOLDED FROM PREMIUM GRADE POLYSTYRENE, K-RESIN OR POLYPROPYLENE.

WE ARE YOUR ONE STOP SOLUTION FOR DROSOPHILA RESEARCH FROM CLONES TO PLASTIC & GLASS WARES. OUR PRODUCTS ARE SAFE AND COST-EFFECTIVE WITH BEST QUALITY.

WE PROVIDE THE FOLLOWING PRODUCTS:

• DROSOPHILA CLONES

• DROSOPHILA VIALS

• DROSOPHILA BOTTLES

• DROSOPHILA PLUGS

• Rapidly tag and convert all small RNAs into detectable cDNA for qPCR

• Simple and robust procedure

• Powerful technology to convert enough RNA to cDNA for up to 5,000 qPCR measurements

• Validate newly discovered MicroRNAs

• Detect and Quantitate siRNAs in knock-down experiments

• Amenable to high-throughput screening of clinical samples including laser-captured micro dissected specimens

• Three reference assays included in each kit: Human U6, Mouse U6 and Human/Mouse miR-16

Simple and effective to use